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Standard Dose Pack

The standard dose is recommended for patients with no known renal impairment (eGFR >90 mL/min) OR mild renal impairment (eGFR ≥60 to <90 mL/min):

  • The standard dose of PAXLOVID is 2 nirmatrelvir 150 mg tablets and 1 ritonavir 100 mg tablet taken together in the morning and at bedtime, with or without food, for 5 days

  • PAXLOVID should be administered at approximately the same time each day for 5 days

Reduced Dose Pack: for patients with moderate renal impairment

The reduced dose is recommended for patients with eGFR ≥30 to <60 mL/min:

  • 1 nirmatrelvir 150 mg tablet and 1 ritonavir 100 mg tablet taken together in the morning and at bedtime, with or without food, for 5 days

  • PAXLOVID should be administered at approximately the same time each day for 5 days

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